BUILD CREATINE

Creatine plays a central role in the body’s energy systems, especially ATP production, which powers both muscle contraction and brain function. However, research shows that the quantity naturally synthesized by the body is insufficient for optimal performance, especially in women undergoing hormonal transitions such as perimenopause and menopause. Studies have shown that creatine supplementation supports lean muscle mass, bone density, and strength in aging women when combined with resistance training. This is especially beneficial for mitigating age-related muscle loss (sarcopenia) and osteoporosis [1].

In addition to its physical benefits, creatine also supports brain energy metabolism. It has shown promise in helping restore cognitive balance and mood stability in women, particularly during hormone-related shifts such as puberty, postpartum, and menopause. Clinical data suggests creatine helps regulate brain energy homeostasis and may reduce symptoms of depression [2]. Emerging research also points to creatine’s therapeutic potential for individuals experiencing energy depletion from conditions like Chronic Fatigue Syndrome, Long COVID, or post-vaccine fatigue. Improvements in fatigue, taste perception, mental clarity, and overall vitality were observed in studies assessing creatine as a supplemental intervention [3]. Specifically, a six-month clinical trial demonstrated that creatine supplementation improved fatigue, breathing capacity, concentration, and reduced headaches and muscle pain in individuals with Long COVID. These findings highlight its potential role in post-viral recovery, as evidenced by research from Food Science & Nutrition [4] and the National Institutes of Health [5].